Accuracy and precision of myocardial T1mapping with MOLLI and ShMOLLI at 1.5T and 3.0T: a phantom study
نویسندگان
چکیده
Background Previous studies have demonstrated that an increase in extracellular volume measured on MRI is directly proportionate to myocardial fibrosis. Myocardial extracellular volume is proportionate to partition coefficient (l) and extracellular volume = l × (1-hematocrit). l can be measured by assessing the T1 relaxation time before and after injection of contrast medium. The goal of this study is to assess the accuracy and precision of several T1 mapping sequences using a phantom at 1.5 and 3.0T.
منابع مشابه
Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold
BACKGROUND T1 mapping allows direct in-vivo quantitation of microscopic changes in the myocardium, providing new diagnostic insights into cardiac disease. Existing methods require long breath holds that are demanding for many cardiac patients. In this work we propose and validate a novel, clinically applicable, pulse sequence for myocardial T1-mapping that is compatible with typical limits for ...
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Methods Ninety-nine subjects with no history of cardiovascular or systemic disease or regular medication underwent native T1 imaging with modified (MOLLI; 3,3,5) and shortened modified look-locker inversion recovery sequence (shMOLLI; 1,1,5) at either 1.5T or 3T. The images were analyzed using an Osirix plug-in with manual motion correction of the ROI placed conservatively within the septal myo...
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